A slacker and a career-driven woman accidentally conceive a child after a one-night stand. As they try to make the relationship work, they must navigate the challenges of parenthood and their differences in lifestyle and maturity.
Media
HD Knocked Up trailer
Cast
Seth Rogen
Ben Stone
Katherine Heigl
Alison Scott
Paul Rudd
Pete
Leslie Mann
Debbie
Jason Segel
Jason
Jay Baruchel
Jay
Jonah Hill
Jonah
Martin Starr
Martin
Lo Mutuc
Jodi
Iris Apatow
Charlotte
Maude Apatow
Sadie
Joanna Kerns
Alison's Mom
Harold Ramis
Ben's Dad
Alan Tudyk
Jack
Kristen Wiig
Jill
Bill Hader
Brent
Ken Jeong
Dr. Kuni
Craig Robinson
Club Doorman
Tim Bagley
Dr. Pellagrino
Loudon Wainwright III
Dr. Howard
Stephanie Mnookin
Dr. Howard's Nurse
Adam Scott
Samuel
J.P. Manoux
Dr. Angelo
Mo Collins
Female Doctor
B.J. Novak
Young Doctor
Tami Sagher
Wardrobe Lady
Brianna Brown
Alison's Friend
Catherine Reitman
Alison's Friend
Nick Thune
Alison's Friend
Paul Feig
Fantasy Baseball Guy
Ben Meyerson
Fantasy Baseball Guy
Wayne Federman
Fantasy Baseball Guy
Melinda Bennett
Dr. Pellagrino's Nurse
Matthew McKane
Club Bartender
Steven Brill
Ben's Boss
Ana Mercedes
Maria
Nadine Griffith
Maternity Nurse at Desk
Diane Schaller
Delivery Nurse
Emersen Riley
Jonah's Girlfriend
Stormy Daniels
Lap Dancer
Nautica Thorn
Lap Dancer
Mary Brill
Real Estate Agent
Lolita Mastrolia
Daughter in Waiting Room
Joseph T. Mastrolia
Father in Waiting Room
Tracy Hartley
Lamaze Instructor
Jeffrey L. Wilson
Record Store Customer
Jessica Alba
Self (uncredited)
Steve Carell
Self (uncredited)
Andy Dick
Self (uncredited)
James Franco
Sol (uncredited)
Eva Mendes
Self (uncredited)
Ryan Seacrest
Self (uncredited)
Dax Shepard
Self (uncredited)
Michelle Woods
Waitress (uncredited)
